In the case of glass type metal oxide surfaces suchas SiO2-TiO2, mainly hydroxyl groups are present, which offer relatively few possibilities for covalent immobilization of biomolecules. To widen the circle of covalent coupling methods, the surface of the waveguide has to be modified by silanization using reactive silane reagents for introducing functionalgroups of all sorts (e.g. aliphatic amine, sulfhydryl, aromatic amine and epoxy) onto the surface of inorganic materials…
In the case of glass type metal oxide surfaces suchas SiO2-TiO2, mainly hydroxyl groups are present, which offer relatively few possibilities for covalent immobilization of biomolecules. To widen the circle of covalent coupling methods, the surface of the waveguide has to be modified by silanization using reactive silane reagents for introducing functionalgroups of all sorts (e.g. aliphatic amine, sulfhydryl, aromatic amine and epoxy) onto the surface of inorganic materials…
